We report that gold-coated nanodisk arrays of nearly micron periodicity have high figure of merit (FOM) and sensitivity necessary for plasmonic refractometric sensing, with the added benefit of suitability for surface-enhanced Raman scattering (SERS), large scale microfabrication using standard photolithographic techniques and a simple instrumental setup. Gold nanodisk arrays were covered with a gold layer to excite the Bragg modes (BM) which are the propagative surface plasmons localized by the diffraction from the disk array. This generated surface-guided modes, localized as standing waves, leading to highly confined fields confirmed by a mapping of the SERS intensity and numerical simulations with 3D finite element method (3D FEM). The optimal gold-coated nanodisk arrays were applied for refractometric sensing in transmission spectroscopy with better performance than nanohole arrays and they were integrated to a 96-well plate reader for detection of IgY proteins in the nM range in PBS. The potential for sensing in biofluids was assessed with IgG detection in 1:1 diluted urine. The structure exhibits a high FOM of up to 46, exceeding the FOM of structures supporting surface plasmon polaritons (SPPs) and comparable to more complex nanostructures, demonstrating that sub-wavelength features are not necessary for high performance plasmonic sensing.
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